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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE4A
All Species:
31.82
Human Site:
Y299
Identified Species:
50
UniProt:
Q14139
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14139
NP_004779.2
1066
122561
Y299
A
Y
L
D
I
L
L
Y
F
T
R
Q
K
D
M
Chimpanzee
Pan troglodytes
XP_001161169
1066
122495
Y299
A
Y
L
D
I
L
L
Y
F
T
R
Q
K
D
M
Rhesus Macaque
Macaca mulatta
XP_001097812
1067
122494
Y299
A
Y
L
D
I
L
L
Y
F
T
R
Q
K
D
M
Dog
Lupus familis
XP_850081
1066
122542
Y299
A
Y
L
D
I
L
L
Y
F
T
R
Q
K
D
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES00
1173
133285
P361
Q
Q
P
S
F
L
V
P
Y
M
L
C
R
N
L
Rat
Rattus norvegicus
Q6P7A2
1066
122361
Y299
A
Y
L
D
I
L
L
Y
F
T
R
Q
K
D
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026081
1074
123247
Y300
T
Y
L
D
M
I
L
Y
F
T
K
Q
K
D
I
Frog
Xenopus laevis
NP_001084506
1072
122544
Y298
T
Y
L
D
L
L
L
Y
C
T
R
Q
K
D
I
Zebra Danio
Brachydanio rerio
XP_001922961
1078
122949
Y304
S
Y
L
E
I
L
L
Y
F
S
R
Q
K
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609060
993
113046
I276
E
F
F
Q
E
L
S
I
N
Q
T
D
E
A
L
Honey Bee
Apis mellifera
XP_393070
965
109934
S255
T
L
L
G
A
L
F
S
L
S
C
L
P
K
T
Nematode Worm
Caenorhab. elegans
Q09349
980
113212
G270
T
P
S
E
K
I
Q
G
R
E
F
G
L
M
S
Sea Urchin
Strong. purpuratus
XP_786748
942
107668
F268
V
W
C
E
I
M
G
F
F
A
R
Q
P
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LF41
1038
117510
F312
S
F
S
T
I
K
N
F
M
N
I
L
Y
S
G
Baker's Yeast
Sacchar. cerevisiae
P54860
961
109887
E251
Q
Q
T
A
M
I
H
E
S
L
Q
A
E
H
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.1
98.6
N.A.
24.6
97
N.A.
N.A.
87.7
79.7
76.7
N.A.
33.1
36.5
22.9
32.7
Protein Similarity:
100
100
98.5
99.4
N.A.
45.2
99
N.A.
N.A.
94.3
90.8
87.4
N.A.
51.3
54.5
42.5
52.2
P-Site Identity:
100
100
100
100
N.A.
6.6
100
N.A.
N.A.
66.6
73.3
73.3
N.A.
6.6
13.3
0
26.6
P-Site Similarity:
100
100
100
100
N.A.
40
100
N.A.
N.A.
93.3
86.6
100
N.A.
26.6
20
13.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.3
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.9
41.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
0
7
7
0
0
0
0
7
0
7
0
7
0
% A
% Cys:
0
0
7
0
0
0
0
0
7
0
7
7
0
0
0
% C
% Asp:
0
0
0
47
0
0
0
0
0
0
0
7
0
54
0
% D
% Glu:
7
0
0
20
7
0
0
7
0
7
0
0
14
0
0
% E
% Phe:
0
14
7
0
7
0
7
14
54
0
7
0
0
0
0
% F
% Gly:
0
0
0
7
0
0
7
7
0
0
0
7
0
0
7
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
0
54
20
0
7
0
0
7
0
0
0
20
% I
% Lys:
0
0
0
0
7
7
0
0
0
0
7
0
54
7
7
% K
% Leu:
0
7
60
0
7
67
54
0
7
7
7
14
7
0
20
% L
% Met:
0
0
0
0
14
7
0
0
7
7
0
0
0
7
34
% M
% Asn:
0
0
0
0
0
0
7
0
7
7
0
0
0
7
0
% N
% Pro:
0
7
7
0
0
0
0
7
0
0
0
0
14
0
0
% P
% Gln:
14
14
0
7
0
0
7
0
0
7
7
60
0
7
0
% Q
% Arg:
0
0
0
0
0
0
0
0
7
0
54
0
7
0
0
% R
% Ser:
14
0
14
7
0
0
7
7
7
14
0
0
0
7
7
% S
% Thr:
27
0
7
7
0
0
0
0
0
47
7
0
0
0
7
% T
% Val:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
54
0
0
0
0
0
54
7
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _